__ Domino

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Possible Answers: FATS.

Last seen on: LA Times Crossword 1 Apr 2018, Sunday

Random information on the term “__ Domino”:

Chinese dominoes are used in several tile-based games, namely, Tien Gow, Pai Gow, Tiu U and Kap Tai Shap. In Cantonese they are called gwat pai (骨牌), which literally means “bone tiles”; it is also the name of a northern Chinese game, where the rules are quite different from the southern Chinese version of Tien Gow.

Ming author Xie Zhaozhe (1567–1624) records the legend of dominoes having been presented to Song Emperor Huizong in 1112. However the contemporary Li Qingzhao (1084 – c. 1155) made no mention of dominoes in her compendium of games. The oldest confirmed written mention of dominoes in China comes from the Former Events in Wulin (i.e. the capital Hangzhou) written by the Yuan Dynasty (1271–1368) author Zhou Mi (1232–1298), who listed “pupai” (gambling plaques or dominoes) as well as dice as items sold by peddlers during the reign of Song Emperor Xiaozong (r. 1162–1189). Andrew Lo asserts that Zhou Mi meant dominoes when referring to pupai, since the Ming author Lu Rong (1436–1494) explicitly defined pupai as dominoes (in regards to a story of a suitor who won a maiden’s hand by drawing out four winning pupai from a set). Tiles dating from the 12th to 14th centuries have survived. Unlike most modern tiles they are white with black and red pips.

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__ Domino on Wikipedia

Random information on the term “FATS”:

Fish acute toxicity syndrome (FATS) is a set of common chemical and functional responses in fish resulting from a short-term, acute exposure to a lethal concentration of a toxicant, a chemical or material that can produce an unfavorable effect in a living organism. By definition, modes of action are characterized by FATS because the combination of common responses that represent each fish acute toxicity syndrome characterize an adverse biological effect. Therefore, toxicants that have the same mode of action elicit similar sets of responses in the organism and can be classified by the same fish acute toxicity syndrome.

During the 1970s, large-scale production of chemicals dramatically increased initiating new legislation to appease public concern about potential harmful effects. After implementation of the Toxic Substances Control Act in 1977, the US Environmental Protection Agency (USEPA) required chemicals, new and existing, to be assessed for risks to human health and ecological systems. Since thousands of new chemicals are registered a year, it is important to utilize a screening technique that predicts toxicity of chemicals in a consistent, efficient manner. As a result, researchers in the field of toxicology focused on the development of QSAR models as a means of assessing toxic effects of chemicals in fish.

FATS on Wikipedia