Catching strategy

This crossword clue is for the definition: Catching strategy.
it’s A 17 letters crossword puzzle definition.
Next time, when searching for online help with your puzzle, try using the search term “Catching strategy crossword” or “Catching strategy crossword clue”. The possible answerss for Catching strategy are listed below.

Did you find what you needed?
We hope you did!.

Possible Answers: TRAP.

Last seen on: LA Times Crossword 29 Jun 2018, Friday

Random information on the term “TRAP”:

2BQ8, 1WAR

54

n/a

ENSG00000102575

n/a

P13686

n/a

NM_001111034NM_001111035NM_001111036NM_001611NM_001322023

n/a

NP_001104504NP_001104505NP_001104506NP_001308952NP_001602

n/a


New Crossword clues and help App now available in the App Store and Google Play Store!
Crossword clues app Android Crossword clues app iphone iOs

Tartrate-resistant acid phosphatase (TRAP or TRAPase), also called acid phosphatase 5, tartrate resistant (ACP5), is a glycosylated monomeric metalloprotein enzyme expressed in mammals. It has a molecular weight of approximately 35kDa, a basic isoelectric point (7.6–9.5), and optimal activity in acidic conditions. TRAP is synthesized as latent proenzyme and activated by proteolytic cleavage and reduction. It is differentiated from other mammalian acid phosphatases by its resistance to inhibition by tartrate and molecular weight.

The mechanism of phosphate ester hydrolysis by TRAP is through a nucleophilic attack mechanism, whereby, catalysis occurs with the binding of a phosphate-substrate to the Fe2+ in the active site of TRAP. This is then followed by a nucleophilic attack by a hydroxide ligand on the bound phosphorus atom, resulting in cleavage of the phosphate ester bond and production of an alcohol. The exact identity and mechanism of the hydroxide ligand is unclear, but it is thought to be either a hydroxide that bridges the metal ions within the active site or a terminal hydroxide bound to Fe3+, with conflicting reports for both mechanisms.

TRAP on Wikipedia