Cholesterol letters

This crossword clue is for the definition: Cholesterol letters.
it’s A 19 letters crossword puzzle definition.
Next time, when searching for online help with your puzzle, try using the search term “Cholesterol letters crossword” or “Cholesterol letters crossword clue”. The possible answerss for Cholesterol letters are listed below.

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Possible Answers: LDL.

Last seen on: LA Times Crossword 28 Nov 2017, Tuesday

Random information on the term “LDL”:

2P4E, 2PMW, 2QTW, 2W2M, 2W2N, 2W2O, 2W2P, 2W2Q, 2XTJ, 3BPS, 3GCW, 3GCX, 3H42, 3M0C, 3P5B, 3P5C, 3SQO, 4K8R, 4NE9, 4NMX, 4OV6

255738

100102

ENSG00000169174

ENSMUSG00000044254

Q8NBP7

Q80W65

NM_174936

NM_153565

NP_777596

NP_705793


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Proprotein convertase subtilisin/kexin type 9 (PCSK9) is an enzyme encoded by the PCSK9 gene in humans on chromosome 1. It is the 9th member of the proprotein convertase family of proteins that activate other proteins.

PCSK9 is ubiquitously expressed in many tissues and cell types. PCSK9 binds to the receptor for low-density lipoprotein particles (LDL), which typically transport 3,000 to 6,000 fat molecules (including cholesterol) per particle, within extracellular fluid.

The LDL receptor (LDLR), on liver and other cell membranes, binds and initiates ingestion of LDL-particles from extracellular fluid into cells, thus reducing LDL particle concentrations. However, when PCSK9 is bound to the LDLR, after the LDLR & LDL particle combination has been ingested, the receptor is degraded and is no longer recycled back to the cell membrane surface to bind and ingest more LDL-particles.

LDL on Wikipedia