Donovan of “Clueless”

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Possible Answers: ELISA.

Last seen on: LA Times Crossword 27 May 2018, Sunday

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Random information on the term “ELISA”:

Immunoscreening is a method of biotechnology to detect a polypeptide produced from a cloned gene.

Clones are screened for the presence of the gene product (a protein). This strategy requires first that a gene library is implemented in an expression vector, and that antiserum to the protein is available. Radioactivity or an enzyme is coupled generally with the secondary antibody. The radioactivity/enzyme linked secondary antibody can be purchased commercially and can detect different antigens. In commercial diagnostics labs, labelled primary antibodies are also used.

ELISA on Wikipedia