gency under the Secy. of Defense

This crossword clue is for the definition: gency under the Secy. of Defense.
it’s A 32 letters crossword puzzle definition.
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Possible Answers: DAF.

Last seen on: LA Times Crossword 6 Apr 19, Saturday

Random information on the term “DAF”:

1H03, 1H04, 1H2P, 1H2Q, 1M11, 1NWV, 1OJV, 1OJW, 1OJY, 1OK1, 1OK2, 1OK3, 1OK9, 1UOT, 1UPN, 2C8I, 2QZD, 2QZF, 2QZH, 3IYP, 3J24, 5FOA

1604

13137

ENSG00000196352

ENSMUSG00000026401

P08174

Q61476

NM_001300903NM_001300904

NM_007827NM_001317361


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NP_000565NP_001108224NP_001287831NP_001287832NP_001287833

NP_001304290NP_031853

Complement decay-accelerating factor, also known as CD55 or DAF, is a protein that, in humans, is encoded by the CD55 gene.[5]

DAF regulates the complement system on the cell surface. It recognizes C4b and C3b fragments that are created during activation of C4 (classical or lectin pathway) or C3 (alternative pathway). Interaction of DAF with cell-associated C4b of the classical and lectin pathways interferes with the conversion of C2 to C2b, thereby preventing formation of the C4b2b C3-convertase, and interaction of DAF with C3b of the alternative pathway interferes with the conversion of factor B to Bb by factor D, thereby preventing formation of the C3bBb C3 convertase of the alternative pathway. Thus, by limiting the amplification convertases of the complementcascade, DAF indirectly blocks the formation of the membrane attack complex.[6]

DAF on Wikipedia