Pain in the neck

This crossword clue is for the definition: Pain in the neck.
it’s A 16 letters crossword puzzle definition.
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Possible Answers: HASSLE.

Last seen on: LA Times Crossword 25 Aug 19, Sunday

Random information on the term “Pain in the neck”:

Carotid artery dissection is a separation of the layers of the artery wall supplying oxygen-bearing blood to the head and brain and is the most common cause of stroke in young adults. (In vascular medicine, dissection is a blister-like de-lamination between the outer and inner walls of a blood vessel, generally originating with a partial leak in the inner lining.)

Dissection may occur after physical trauma to the neck, such as a blunt injury (e.g. traffic collision), strangulation or chiropractic manipulation, but may also happen spontaneously.

The signs and symptoms of carotid artery dissection may be divided into ischemic and non-ischemic categories:

Non-ischemic signs and symptoms

Ischemic signs and symptoms

The causes of internal carotid artery dissection can be broadly categorised into two classes: spontaneous or traumatic.

Once considered uncommon, spontaneous carotid artery dissection is an increasingly recognised cause of stroke that preferentially affects the middle-aged.

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Pain in the neck on Wikipedia

Random information on the term “HASSLE”:

In bioinformatics, BLAST (basic local alignment search tool) is an algorithm for comparing primary biological sequence information, such as the amino-acid sequences of proteins or the nucleotides of DNA and/or RNA sequences. A BLAST search enables a researcher to compare a query sequence with a library or database of sequences, and identify library sequences that resemble the query sequence above a certain threshold.

Different types of BLASTs are available according to the query sequences. For example, following the discovery of a previously unknown gene in the mouse, a scientist will typically perform a BLAST search of the human genome to see if humans carry a similar gene; BLAST will identify sequences in the human genome that resemble the mouse gene based on similarity of sequence.

BLAST, which The New York Times called the Google of biological research, is one of the most widely used bioinformatics programs for sequence searching. It addresses a fundamental problem in bioinformatics research. The heuristic algorithm it uses is much faster than other approaches, such as calculating an optimal alignment. This emphasis on speed is vital to making the algorithm practical on the huge genome databases currently available, although subsequent algorithms can be even faster.

HASSLE on Wikipedia