Small cells

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Possible Answers: AAAS.

Last seen on: LA Times Crossword 4 Nov 18, Sunday

Random information on the term “Small cells”:

Small-cell carcinoma (also known as small-cell lung cancer, or oat-cell carcinoma) is a type of highly malignant cancer that most commonly arises within the lung,[1] although it can occasionally arise in other body sites, such as the cervix,[2] prostate,[3] and gastrointestinal tract. Compared to non-small cell carcinoma, small cell carcinoma has a shorter doubling time, higher growth fraction, and earlier development of metastases.

Small-cell carcinoma of the lung usually presents in the central airways and infiltrates the submucosa leading to narrowing of bronchial airways. Common symptoms include cough, dyspnea, weight loss, and debility. Over 70% of patients with small-cell carcinoma present with metastatic disease; common sites include liver, adrenals, bone, and brain.

Due to its high grade neuroendocrine nature, small-cell carcinomas can produce ectopic hormones, including adrenocorticotropic hormone (ACTH) and anti-diuretic hormone (ADH). Ectopic production of large amounts of ADH leads to syndrome of inappropriate antidiuretic hormone hypersecretion (SIADH).


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Small cells on Wikipedia

Random information on the term “AAAS”:

Coordinates: 42°22′51″N 71°06′37″W / 42.380755°N 71.110256°W / 42.380755; -71.110256

The American Academy of Arts and Sciences is one of the oldest learned societies in the United States. It is devoted to the advancement and study of the key societal, scientific, and intellectual issues of the day.

Membership in the academy is achieved through a thorough petition, review, and election process and has been considered a high honor of scholarly and societal merit[1] ever since the academy was founded during the American Revolution by John Adams, John Hancock, James Bowdoin,[2] and others of their contemporaries who contributed prominently to the establishment of the new nation, its government, and the United States Constitution.[3]

Today the Academy is charged with a dual function: to elect to membership the finest minds and most influential leaders, drawn from science, scholarship, business, public affairs, and the arts, from each generation, and to conduct policy studies in response to the needs of society. Major Academy projects now have focused on higher education and research, humanities and cultural studies, scientific and technological advances, politics, population and the environment, and the welfare of children. Dædalus, the Academy’s quarterly journal, is widely regarded as one of the world’s leading intellectual journals.[4]

AAAS on Wikipedia