Toward the tiller

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Possible Answers: AFT.

Last seen on: LA Times Crossword 23 Apr 19, Tuesday

Random information on the term “AFT”:

In the statistical area of survival analysis, an accelerated failure time model (AFT model) is a parametric model that provides an alternative to the commonly used proportional hazards models. Whereas a proportional hazards model assumes that the effect of a covariate is to multiply the hazard by some constant, an AFT model assumes that the effect of a covariate is to accelerate or decelerate the life course of a disease by some constant. This is especially appealing in a technical context where the ‘disease’ is a result of some mechanical process with a known sequence of intermediary stages.


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In full generality, the accelerated failure time model can be specified as

where θ {\displaystyle \theta } denotes the joint effect of covariates, typically θ = exp ⁡ ( − [ β 1 X 1 + ⋯ + β p X p ] ) {\displaystyle \theta =\exp(-[\beta _{1}X_{1}+\cdots +\beta _{p}X_{p}])} . (Specifying the regression coefficients with a negative sign implies that high values of the covariates increase the survival time, but this is merely a sign convention; without a negative sign, they increase the hazard.)

AFT on Wikipedia